Research Projects

This research focuses on understanding space deconditioning and developing comprehensive systems to mitigate the adverse physiological effects of microgravity on astronauts.

Spaceflight-induced deconditioning presents a major challenge to human health during and after long-duration missions, contributing to muscle atrophy, bone loss, cardiovascular dysfunction, and sensorimotor impairment. This research investigates the underlying mechanisms of physiological decline in microgravity and evaluates integrated mitigation strategies using a combination of ground-based analogs (e.g., head-down tilt, LBNP), biomechanical modeling, and real-time physiological monitoring. By developing a modular countermeasure system — featuring tools like the Lower Extremity Force Acquisition System (LEFAS) and personalized exercise protocols — we aim to preserve musculoskeletal and cardiovascular integrity throughout space missions. The findings contribute to NASA’s broader efforts in preparing astronauts for lunar and Mars exploration.