ERBAL Research Group

The hostile environment of space has adverse short- and long-term effects on the human body, specifically causing muscle atrophy, bone decalcification and poor cardiovascular endurance. This research aims to effectively reduce the gap between precondition and postcondition syndrome by exploring how space conditions affect human physiology, including studies on intraocular pressure and countermeasures for space deconditioning. This work, supported by ERBAL, provides critical insights for developing solutions to biomedical challenges in space.

Primary Investigator

• Christine Dailey Walck, Ph.D., Assistant Professor of Mechanical Engineering, Embry-Riddle Aeronautical University

Co-Investigators

• Melanie Coathup, Ph.D., Professor and Director of the Biionix Cluster, College of Medicine, Univeristy of Central Floida
• Cagri Kilic, Ph.D., Assistant Professor of Aerospace Engineering, Embry-Riddle Aeronautical University
• Eduardo Divo, Ph.D., Professor and Chair, Mechanical Engineering Department, Embry-Riddle Aeronautical University
• Victor Huayamave, Ph.D., Assistant Professor of Mechanical Engineering, Embry-Riddle Aeronautical University
• Alesha Fleming, D.C., Doctor of Chiropractic Medicine, Embry-Riddle Aeronautical University
• Susan Jewell, M.D., CEO and Co-Founder of Mars-Moon Astronautics Academy and Research (MMAARS)
• Foram Madiya, Ph.D., Assistant Professor of Physical Sciences, Embry-Riddle Aeronautical University
• Amber Paul, Ph.D., Assistant Professor of Human Factors and Behavioral Neurobiology, Embry-Riddle Aeronautical University
• Cassandra Juran, Ph.D., Assistant Professor of Aerospace Physiology, Embry-Riddle Aeronautical University
• Emel Sen Kilic, Ph.D., Assistant Professor of Aerospace Physiology, Embry-Riddle Aeronautical University 

Funding

• Embry-Riddle’s Faculty Innovative Research in Science and Technology (FIRST) Program 2020-2021
• Florida Space Grant Consortium 2020-2021
• National Science Foundation- Research Experiences for Undergraduates (REU): NSF 19-582 (2022-2025)

Patents

• Walck, C. D. (2017). Biomechanics device for use in space missions (U.S. Patent No. 9789356B2). https://patents.google.com/patent/US9789356B2/en

Partners

• The Microgravity Centre (Centro de Microgravidade), Pontifical Catholic University of Rio Grande do Sul - Porto Alegre, Brazil
• U.S. Naval Research Lab, Edison Program - Washington, D.C.

At ERBAL, we are committed to breaking new ground in computational modeling for musculoskeletal (MSK) systems. Our research aims to enhance predictive capabilities, laying the foundation for next-generation models that can address critical biomedical challenges. Utilizing machine learning and artificial intelligence, this area predicts physiological changes caused by environmental conditions. A notable project integrates machine learning with proteomic analysis to enhance the prediction of musculoskeletal changes, building on findings from aerospace biomedical engineering.

Vision for MSK Modeling

Musculoskeletal systems are incredibly dynamic, responding to environmental, mechanical, and pathological factors. However, traditional MSK models often fall short in capturing these adaptive processes. At ERBAL, we are focused on integrating advanced machine learning techniques with biological data to address this gap. Our goal is to evolve static models into predictive tools capable of simulating muscle adaptations, force generation, and structural changes under various conditions.

Driving Innovation With Machine Learning

Our research leverages cutting-edge neural network architectures and proteomic analyses to predict skeletal muscle responses. By combining deep learning with biological insights, we are developing a framework to simulate muscle atrophy progression and evaluate countermeasures. This approach not only enhances our understanding of muscle adaptation but also sets the stage for impactful advancements in rehabilitation and healthcare.

Applications in Extreme Environments

Our work is particularly relevant for addressing physiological challenges in extreme environments, such as space exploration. The methodologies we are developing have potential applications in mitigating muscle and bone loss experienced during prolonged spaceflight, as well as in addressing conditions like sarcopenia and immobilization-induced atrophy here on Earth.

Collaborative and Interdisciplinary Efforts

ERBAL’s research is supported by a robust interdisciplinary approach, bridging engineering mechanics and biological sciences. By fostering collaborations with institutions like the University of Central Florida and leveraging state-of-the-art facilities, we aim to push the boundaries of what is possible in predictive MSK modeling.

Looking Ahead

Through our work, ERBAL is paving the way for transformative breakthroughs in MSK research. By refining our models and expanding their predictive capabilities, we aim to provide the scientific community with powerful tools for understanding and addressing musculoskeletal disorders.

Collaborations

Melanie Coathup, Ph.D.
Professor and Director of the Biionix Cluster 
University of Central Florida 

Bryan Bourcier, SCS
Director of Quality and Innovation, Sports Med & Rehab
AdventHealth

Cassandra Juran, Ph.D.
Assistant Professor of Aerospace Physiology
Embry-Riddle Aeronautical University

Emel Sen Kilic, Ph.D.
Assistant Professor of Aerospace Physiology
Embry-Riddle Aeronautical University

ERBAL is proud to collaborate with Qforensics, a leader in crash reconstruction and forensic biomechanics. This partnership combines ERBAL’s advanced expertise in biomechanics, human performance, and motion analysis with Qforensics' industry-leading knowledge in crash reconstruction and injury biomechanics. Together, we aim to push the boundaries of forensic science by applying biomechanical principles to real-world case studies, offering innovative solutions to complex forensic investigations.

Crash Reconstruction Analysis

Using motion capture, imaging, and computational tools, ERBAL and Qforensics work together to reconstruct crash events, analyzing occupant kinematics, injury mechanisms, and biomechanics to provide accurate forensic insights.

Forensic Casework

By applying biomechanical modeling and crash data analysis, the partnership supports law enforcement, attorneys, and insurance companies in resolving forensic cases with a high degree of scientific rigor.

Educational Opportunities

This collaboration also serves as a rich learning environment for students at Embry-Riddle, allowing them to engage in hands-on projects that bridge academia and real-world forensic applications.

This research develops autonomous systems, space-deconditioning countermeasures, and assistive technologies. It includes efforts in robotic logistics automation and rehabilitation systems extending the knowledge gained from aerospace biomedical research and predictive modeling while using biomechanics, computer science, imaging and neuroscience to analyze muscle function, study human movement, enhance medical rehabilitation protocols and optimize human performance.

Adaptive Solutions

At ERBAL, we are dedicated to empowering individuals with disabilities by advancing rehabilitation through innovative solutions. Whether it’s fostering participation in adaptive sports or enhancing social engagement, our mission is to bridge the gap between accessibility and opportunity. 

For instance, one of our cutting-edge assistive devices is designed to support paraplegic individuals in adaptive sports by facilitating forward stroke movements. Unlike traditional equipment, this device actively guides users to complete forward strokes, providing therapeutic support akin to a physical therapist. Beyond movement assistance, it promotes passive stretching to enhance mobility and flexibility. By integrating rehabilitation with performance, this technology opens new avenues for adaptive sports enthusiasts, empowering them to reach their full potential.

Sport Biomechanics

At ERBAL, we are committed to advancing the field of sports biomechanics by conducting research that bridges the gap between science and athletic performance. Through innovative studies, we aim to optimize movement, improve injury prevention,and enhance recovery strategies for athletes across various disciplines.

Musculoskeletal Modeling

Our musculoskeletal modeling research focuses on developing advanced computational tools and methods to simulate and analyze the complex interactions within the human body. These efforts aim to improve our understanding of musculoskeletal biomechanics, optimize movement, and provide innovative solutions for rehabilitation and clinical applications.

Dynamic Modeling

Focuses on understanding and simulating the mechanical behavior of complex biological systems to address clinical challenges and improve patient outcomes. Through advanced computational methods, we aim to develop innovative solutions that bridge the gap between biomechanics and clinical practice.